Searchable abstracts of presentations at key conferences in endocrinology

ea0024oc1.5 | Oral Communications 1 | BSPED2010

Factors affecting changes in insulin sensitivity and insulin secretion during Growth Hormone treatment in children born small for gestational age

Thankamony A , Jensen R B , O'Connell S , Kirk J M W , Donaldson M D C , Ivarsson Sten-A , Soder O , Hoey H , Juul A , Dunger D B

Background: Individuals born Small for Gestational age (SGA) are at high risk of development of type 2 diabetes. Growth hormone (GH) therapy can also adversely affect glucose metabolism.Aim: To explore the factors associated with changes in insulin sensitivity (IS) and insulin secretion during one year of GH treatment in children born SGA.Methods: In the NESGAS clinical trial, we studied 82 (55♂) pre-pubertal children (age 3....